How does xyy syndrome happen

Instead, it is typically caused by a random event that happens during the formation of a sperm cell before conception when the sperm fertilizes the egg. Even though this random event occurs in the sperm cell of the father of a person with 47, XYY syndrome, the syndrome is not inherited from the father because the father himself typically does not have the syndrome.

If a couple has a child with 47, XYY syndrome, the chances for the couple or family members to have another child with the syndrome are not increased. Men who have 47, XYY syndrome themselves are also not thought to be at an increased risk to have a child with chromosome differences. Some sperm cells of a man with 47, XYY syndrome will have an extra Y chromosome. However, it is thought that these cells are less likely to be able to survive to fertilize an egg. Therefore, the chances for a man with 47, XYY syndrome to have a child with a sex chromosome abnormality are not thought to be increased.

Diagnosis Diagnosis. A doctor may then order testing to see if there is a genetic explanation for the signs and symptoms. Tests that may be ordered include: [2] Karyotype : a test that is used to view all the chromosomes in a cell Chromosomal microarray : a test that looks for extra or missing chromosomes or pieces of chromosomes In some cases, 47, XYY syndrome may be suspected prenatally based on routine screening tests.

A diagnosis can be confirmed with prenatal tests such as an amniocentesis or chorionic villus sampling CVS. Treatment Treatment. The signs and symptoms of 47, XYY syndrome can be managed with a variety of therapies. Occupational therapy may be recommended for infants and young boys who have low muscle tone hypotonia , and speech therapy may be recommended for boys who have speech delay.

Boys with 47, XYY syndrome may be in special education at school, or they may have extra help in some classes. If autism spectrum disorder is present, applied behavioral analysis ABA therapy may be recommended. Prognosis Prognosis. The long-term outlook for people with 47, XYY is typically good. Boys with this syndrome can do well both in school and in building social relationships. Men with 47, XYY syndrome can also have successful careers and families of their own.

Organizations Organizations. Organizations Supporting this Disease. Social Networking Websites. Do you know of an organization? Learn More Learn More. Click on the link above to view this information. This website is maintained by the National Library of Medicine. The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

Click on the link above to view this information page. In-Depth Information The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health.

Visit the website to explore the biology of this condition. Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss 47, XYY syndrome.

Click on the link to view a sample search on this topic. Submit a new question 47,XYY syndrome was present in my first delivery. See answer I have a 4 year old son who was diagnosed with XYY karotype about a year ago.

See answer Have a question? References References. Genetics Home Reference. Ross J and Bishop D. Lenroot RK. XYY Syndrome. National Organization for Rare Disorders. Oral, physical, and behavioral aspects of patient with chromosome 47, XYY syndrome. October-December ; 33 4 Clinical aspects of infertile 47,XYY patients: a retrospective study.

Human Fertility. Positive effects of early androgen therapy on the behavioral phenotype of boys with 47,XXY. June ; 2 Do you know of a review article? Share this content:. Close Copy Link.

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A small number of boys may have increased testicular size for their age, or have an increased risk for asthma and seizures. Many boys with XYY syndrome are healthy and have no obvious symptoms. So sometimes the condition isn't diagnosed or is found when a doctor checks for a different issue. Often, XYY syndrome is found because parents talked with a doctor about concerns with their son's development.

This can help boys receive a diagnosis early. Research has shown that early interventions and treatments are more effective. To diagnosis XYY syndrome, doctors check a blood sample for the extra Y chromosome. Before birth, the condition may be found through karyotype test chromosomal analysis or noninvasive prenatal testing NIPT. NIPT is done on the fluid surrounding the fetus, tissue from the placenta, or the blood from the mother.

After birth, doctors can make a diagnosis with a karyotype or with a microarray test from the baby. Finding services early is important and can greatly increase their ability to help boys live a healthier, more productive life. Options vary greatly depending on how old a boy is at the time of his diagnosis, whether he has noticeable symptoms, and the severity of those symptoms.

Regular doctor visits. At periodic visits, a doctor can monitor a boy's development for delays, social and language disabilities, or health problems and treat these promptly.

Educational support services. Educational support can teach boys ways to keep pace in school. Some might be eligible for an individualized educational program IEP or education plan , which are designed to help children with special needs. Early intervention services. It can be very helpful and often more effective for a boy to have speech , occupational , physical , or developmental therapy in the early months of life or as soon as concerns are found.

Speech therapy and physical therapy can improve a boy's speaking, reading, and writing skills and help increase strength and coordination. As children get older, physical symptoms of XYY syndrome can include: 1 ,2. However, because these characteristics tend to fall within the normal range for males, often those with XYY syndrome do not get diagnosed. Developmental signs of the syndrome may include: 2, 4.

Most cases of XYY syndrome are not inherited, and the syndrome occurs randomly in pregnancies of women from all ages and ethnic backgrounds. Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person will develop male or female sex characteristics. Since there is often no medical reason to test for XYY syndrome, the diagnosis is commonly never made. If prenatal diagnosis is not done, a physician can diagnose XYY syndrome on a person by performing a clinical evaluation, patient history, and specialized tests, such as a karyotype, which is the most common test, to detect the presence of an extra Y chromosome.

Boys may also be diagnosed because of learning problems, developmental delay, or behavioral issues. Those with XYY can expect to have a good long-term outlook. Boys can do well in school and in building relationships, while adults with the syndrome can have successful careers and families. There is no treatment for XYY syndrome, and it is a lifelong condition. However, boys and men with XYY can live normal lives and seek help for particular symptoms, such as learning or developmental delays through speech therapy, occupational therapy, or other assistance.

There is no treatment for XYY syndrome. However, medication and therapies can help with symptoms and complications of the condition.